Pathology of interstitial lung diseases

نویسنده

  • Arne Warth
چکیده

In general, the first approach to a histological diagnosis is the categorization of morphological findings according to the current standard into ontogenetic, circulatory, inflammatory, tumor-like, and neoplastic lesions. Furthermore, it needs to be addressed if and to which extent specific changes are evident in defined anatomical structures such as the pleura, the alveolae and their structure, bronchi and bronchioli, and vessels. The distribution of morphological changes within these structures are important clues to the genesis of the disease, thus, relevant findings need to be categorized as either diffuse, focal, heterogeneous etc. Next, the extent and the composition of the cellular immune reactions need to be assessed in detail. Finally, the specimens must be thoroughly screened for specific findings like granulomas, fibroblast foci, birefringent material, microorganisms etc.

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تاریخ انتشار 2016